|Two depictions of “chemistry” themed wedding cakes: an equation of love (left) design and a chemistry of love (right) design; the wedding being a celebration and official public announcement of the marriage, i.e. official chemical bond formation.|
In 1459, Johann Andreae is attributed to have penned Chymical Wedding of Christian Rosenkreutz, a mixture of alchemy and Christianity, and allegorical romance story about the way Christian Rosenkreuz was invited to go to a wonderful castle full of miracles, in order to assist the “Chymical Wedding” of the king and his new bride. (Ѻ)
In 1948, American writer Thomas Dreier stated that marriage is largely a matter of chemistry: 
“Why is it that in some homes husbands and wives live together harmoniously, and in others they lead a dog-and-cat existence? It is largely a matter of human chemistry.”
In the 1970s, American mathematical psychologist John Gottman determined the ratio (5-to-1) of attraction-to-repulsion found in successful long-term marriage bonds.  In 2003, internet writer Wild Bob gave the following opinion on the scientific determination of marriage: 
“It’s not chemistry that determines long-term love—it’s thermodynamics.”
With the rise of the internet, engineers (e.g. ScientificMatch.com or eChemistry.com), sociologists (e.g. eHarmony.com or PerfectMatch.com), psychologists (e.g. Match.com), and anthropologists (e.g. Chemistry.com) have been developing and testing theories at various dating sites to attempt to match people, scientifically.
In 2014, a study (Ѻ), conducted at the Max Planck Institute for Ornithology, Seewiesen, Germany, of a popular of 160 zebra finches, allowed half the birds to pair of naturally, i.e. naturally chosen-parings, and the other half being “forcibly paired”, finding that the survival rate in the naturally-pairings of chicks was 37% higher.
1. Dreier, Thomas. (1948). We Human Chemicals: the Knack of Getting Along with Everybody (pg. 53). Updegraff Press.
2. (a) Gottman, John. (1994). Why Marriages Succeed or Fail. New York: Fireside.
(b) Gottman, John M., Murray, James D., Swanson, Catherine, Tyson, Rebecca, and Swanson, Kristin R. (2005). The Mathematics of Marriage: Dynamic Nonlinear Models. MIT Press.
3. (a) Thims, Libb. (2007). Human Chemistry (Volume One), (pg. 423). Morrisville, NC: LuLu.
(b) Wild Bob. (2003). “Thermodynamics of Love”, Jan 31, UnsolvedMysteries.com.
● Marriage – Wikipedia.