Space

Karman line (outerspace) 2
In 1663, Otto Guericke, after making experimental vacuums, stated that atmosphere has pressure, and that at a certain height above the earth, space or a pure vacuum exists. [3]
In science, space is a place empty of matter; the region between things; generally, a void or vacuum.

Quotes
The following are related quotes:

“The totality consists of bodies and space. The fact of sensation itself universally attests that there are bodies, and it is by reference to sensation that we must rationally infer the existence of imperceptible bodies. If what we call ‘void’ or ‘space’ or ‘impalpable being’ were nonexistent, bodies would not have anywhere to exist, nor would they have a medium through which to move, as they manifestly do.”
Epicurus (c.350BC), “Letter to Herodotus”; as translated by George Strodach (1963) in Epicurus: the Art of Happiness (pg. 93) [1]

“Could empty space exist, and is heavenly space unbounded?”
Otto Guericke (c.1647), mental note; in Magdeburg Experiments on the Existence of the Vacuum (pg. #)

“Even though a vacuum in a strictly scientific sense cannot be produced here on earth, nonetheless we perceive the reason, for clearly, the effluences of matter prevent this. Where substances are no longer found, however, far above the earth, there will be no effluence of things. With the cause lacking, the effect is absent. Consequently, space must be empty. Would it not be more rational to hold that whether or not there is an intermediate substance or not, that ‘space’, nonetheless, exists and endures, independent of motion and rest and that it makes no difference whether anything corporeal is present in it or not?”
Otto Guericke (1663), Magdeburg Experiments on the Existence of the Vacuum (pg. 132)

“The advantage of the principle of least action is that in one and the same equation it relates the quantities that are immediately relevant not only to mechanics but also to electrodynamics and thermodynamics; these are space, time, and potential.”
Max Planck (c.1910), Publication [2]

References
1. Epicurus. (c.350BC). Epicurus: the Art of Happiness (translator: George Strodach) (pg. 93). Penguin, 2012.
2. Myint-U, TYn, and Debnath, Lokkenath. (2007). Linear Partial Differential Equations for Scientists and Engineers (pdf) (pg. vii). Springer, 2011.
3. Guericke, Otto. (1663). The Vacuum of Space (De Spatio Vacuo). Unpublished; New Magdeburg Experiments on the Vacuum of Space (Ottonis De Guericke Experimenta Nova (ut vocantur) Magdeburgica de Vacuo Spatio) (preface, pdf) (pg. 132). Janssonius a Waesberge, 1672.

See also
Spacetime

External links
Space – Wikipedia.

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